Malabsorption and Growth Failure Due to Intestinal Enterokinase Deficiency
نویسندگان
چکیده
منابع مشابه
Intestinal enterokinase deficiency.
Enterokinase is an enzyme secreted by the mucosa of the small intestine and is responsible for the conversion of trypsinogen to its active product, trypsin. Its key role in initiating the formation of proteolytic enzymes from their inactive precursors is illustrated in Fig. 1. When the pancreatic zymogens reach the duodenum, trypsin is formed by the action of enterokinase on trypsinogen and thi...
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Intestinal enterokinase deficiency in 2 sibs in described. A boy failed to gain weight and had vomiting, diarrhoea, oedema, hypoproteinaemia, and anaemia in early infancy. His duodenal juice contained very low or absent proteolytic enzyme activity, which increased markedly after addition of enterokinase. He was treated with pancreatic extract and gained weight rapidly. At 44 months of age he is...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1970
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197009000-00167